polyadenylic acid การใช้

The name " poly ( A ) tail " ( for polyadenylic acid tail ) reflects the way RNA nucleotides are abbreviated, with a letter for the base the nucleotide contains ( A for adenine, C for cytosine, G for guanine and U for uracil ).
To generate an assay for PrP Sc in blood that is both highly sensitive and specific, the researchers used limited serial PMCA ( sPMCA ) with SOFIA . They did not find any enhancement of sPMCA with the addition of polyadenylic acid, nor was it necessary to match the genotypes of the PrP C and PrP Sc sources for efficient amplification.
Until 2015, all known mammalian prion diseases were caused by the so-called prion protein, PrP, when Multiple System Atrophy was found to be likely caused by a new prion called Alpha-synuclein, The precise structure of the prion is not known, though they can be formed by combining PrP C, polyadenylic acid, and lipids in a Protein Misfolding Cyclic Amplification ( PMCA ) reaction.